To answer this question, we have to consider the way Manifest Destiny and imperialism have evolved over time. Initially, Manifest Destiny was the expansion of the United States across the North American continent. While that's shifted to an expansion of US businesses based around the world, it's also influenced the way individual US-based companies work.
On a smaller scale, Manifest Destiny has become the theoretically justified expansion of individual companies within the US. Take, for example, oil companies. They find a rich plot of land that would be good for their business and justify taking it to further their company expansion—similar to how the US originally expanded from east to west. They're constantly looking for plots of land in unclaimed areas, so to speak—somewhere they can expand their business and thrive without the interference from a competitor.
Imperialism is a bit in the same vein when we look at it as confined within the US. Company CEOs and business leaders use their power to expand their businesses to certain regions, sometimes competing with each other to get the land. We also have to look a bit at politics and how people running for office seats (ranging anywhere from town mayor to seats in Congress to the president) use their influence to garner votes and support from the people. The government offices are in and of themselves workplaces, ones where diplomatic influence holds great weight.
So, Manifest Destiny has shifted to a larger expansion of American workplaces growing across the world. But both Manifest Destiny and imperialism also affect how our government works and even how US-based businesses establish their growth within the continent.