The main themes in Samuel Beckett's Waiting for Godot circulate around the ideas of salvation, absurdism, the human condition, and waiting (as openly stated in the title of the play). That said, all of these themes also tie in to the ideas of social and political change.
Salvation is represented through Vladimir's (Didi) and Estragon's (Gogo) belief that Godot will be their salvation. Without Godot, both characters feel as though they have no purpose in life, outside of waiting for Godot. For them, presently, their only purpose is waiting for Godot to show up, telling them what they are to do from the point of the meeting on. Socially, for them both, they have no greater purpose than this. Their entire future lies in the meeting with Godot. Therefore, their social change will only come once the meeting has taken place. They are unable to leave their current place in life, both physical and figurative, until Godot appears:
Gogo: Let's go.
Didi: We can't.
Gogo: Why not?
Didi: We're waiting for...
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