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Having just committed the murder of Duncan, Macbeth is portrayed in this scene as still being filled with doubt and remorse. He relates to his wife that he thinks he heard a voice that cried, among other things, "Macbeth shall sleep no more" because of the deeds he has committed. This is somewhat prophetic, though not as much as Lady Macbeth's suggestion that he stop thinking such thoughts, because "it will make us mad." His wife seizes the initiative, going to smear blood on Duncan's grooms so as to make them appear guilty. Macbeth seems to regret what he has done, and his wife mocks him for it. He even says at the end of the scene that he wishes he could wake Duncan by knocking at his door. His humanity, which will not be so apparent at the end of the play, is very much in evidence in this scene.
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