How the enzyme function in the liver would be affected in a person with cirrhosis?

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dano7744 | College Teacher | (Level 2) Educator

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Cirrhosis of the liver is a chronic disease that adversely affects the overall physiology of the organ. The liver has many important functions, one function is detoxifying the blood before the blood enters systemic circulation.

Enzymes are chemical catalyst's that assist biochemical reactions in the body. When the liver is damaged, as in cirrhosis, the number of liver enzymes are elevated because the enzymes are trying to make the organ function normally. There are many liver enzymes, one of which is SGOT (serum glutamic oxaloacetic transaminase). SGOT levels rise dramatically in the presence of liver disease. Enzyme levels rise when the hepatic cells and tissues are damaged.

Even though the number of liver enzymes are elevated in cirrhosis, they are unable to complete their function due to the state of disease.

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