From the very beginning of his life, Nwoye was not at all the manly type of son that Okonkwo wished he would be. He was not as interested in wrestling, or as good at it. He does not want to grow up to get titles and be the type of man that Okonkwo wishes he would be. In some ways he reminds Okonkwo of his father, which is terribly disappointing.
As Ikemefuna and Nwoye get closer as time goes on, Nwoye actually tries to get more into the things that Okonkwo wants him to because he is so fond of Ikemefuna.
After Ikemefuna's death, Nwoye is angrier and angrier with his father and starts to push farther and farther away, eventually joining the Christians and basically putting an end to the relationship with his father.