At the beginning of the chapter, they react with a bit of annoyance, but nothing too bad. They all react the same way, of course. The narrator says that they are all saying pretty much the same thing. But there are only two voices -- they are all just two sets of "twins," it seems.
As I say, they are only slightly annoyed, asking John "Who are you pushing? Where do you think you're going?" But when the soma comes out, they forget about John. It is not until he stops the soma distribution that they really get angry.