Please see the link below for another answer. Also, you might want to check out the free eNotes guide called, "How to Write a Compare-and-Contrast Essay".
I'm assuming you meant how do you contrast Victor and the creature, since Frankenstein is Victor's last name. Only through pop and media culture has society begun to think of the creature as actually begin named Frankenstein, so be careful.
As far as how the two are contrasted, one way to look at it their individual ways of thinking. Victor tends to lean more towards an emotional thought process. For instance, he becomes so blinded by his ambition while creating the creature that he doesn't even notice what the creature is beginning to look like. Nor does he think through any possible negative consequences. The creature, however, tends to use a much more rational thought process, planning out his actions and his arguments with precision.