When automobiles first came to be manufactured on a large scale, they destroyed some jobs, but created many others. On the whole, they led to the creation of more jobs than they destroyed.
Think about all the jobs that were no longer necessary once automobiles took over. There was no longer nearly as much need for stable workers and farriers. There was much less need for harness makers and carriage makers. All of these sorts of jobs were destroyed by cars.
On the other hand, think of all the new kinds of jobs that came into existence. There was a need for people to make the cars, of course. But there was also a need for people to extract and refine oil. There was a need for gas stations. There was a need for people to build roads for the automobiles to drive on. All of these sorts of jobs were created, making up for the jobs destroyed by the reduced use of horses.