There is no way to know exactly what killed Alexander. All we have to go on is contemporary accounts from a time when no one knew very much at all about medicine. Many of those accounts might be embellished or even completely fictional. No one even knows where Alexander is buried (if he was buried) so there is no way to even dig up his bones and to test them.
What many historians believe today is that he died from some sort of illness. They believe that it might have been typhoid or perhaps malaria. Of course, this is just speculation. Others speculate that Alexander was poisoned, but most discount this possibility.
The bottom line is that this was too long ago for us to have any real way to know.
on either 10th or 11th of june 323 BC. Details of his death differ slightly. some say he kept drinking wine for two days and was struck by a fever which killed him
According to the University of Maryland School of Medicine report of 1998, Alexander probably died of typhoid fever.n the week before Alexander's death, historical accounts mention chills, sweats, exhaustion and high fever, typical symptoms of infectious diseases, including typhoid fever.
Previous most popular theories hold that Alexander either died of malaria or was poisoned.
Alexander died between the evening of June 10 and the evening of June 11, 323 BC.This happened in the palace of Nebuchadnezzar II in Babylon.