The title says everything about the perspective that Joe Keller ought to have had on humanity but chose not to adopt out of greed. He should've realized that he had a great responsibility to all the airmen who'd rely upon the aircraft engine parts he supplied. In that sense, he should've regarded those airmen as if they were his own sons and protected them accordingly. But he didn't. Instead, he ignored their safety and welfare in pursuit of the almighty dollar.
The title of the play also implies a greater responsibility to humankind as a whole. Miller appears to be suggesting how important it is for us to realize that we all have a duty to look out for each other. And the headlong pursuit of wealth, as so tragically illustrated in the case of Joe Keller, represents a serious dereliction of this duty.