How to calculate ANC? *supported with evidence

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mvcdc eNotes educator| Certified Educator

ANC refers to Absolute Neutrophil Count. Neutrophils consist of around 50-70% of the white blood cells and are responsible for fighting off infections. The normal level is usuall 1000-1500 cells/uL or above. A lower ANC means the person has neutropenia. Since they have a lower number of infection-fighting cells, these individuals are more susceptible to diseases.

ANC cannot be measured directly, but can be calculated from CBC (complete blood count), by getting the neutrophil in the differential using certain formulas. There are two kinds of neutrophils: polys or bands, and both should be taken into account.

`ANC = ((%polys + % b a n d s)*WBC)/100` or

`ANC = (a b s o l u t e p o l y s + a b s o l u t e b a n d s)*1000`



If a person has an absolute neutrophil at 0.46 and absolute bands at 0.08, his/her ANC will be (0.46 + 0.08)*1000 = 540. This is a low ANC. 


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