Discrimination is when a person is prejudiced against based upon a specific group to which they belong.
Curley's wife, in John Steinbeck's novel Of Mice and Men, is most certainly discriminated against in the novel.
First, the fact that Steinbeck "refuses" to give Curley's wife a name is an example of discrimination. She is not a woman in her own right. Instead, she is considered property of Curley's--given that she is referred to as "Curley's wife."(The first time Curley's wife is spoken of appears on page 14 of the electronic text found on the web. It appears in chapter two.)
Second, since Curley's wife is the only woman seen in the text (the only others are the two women who run the flop houses), many of the men are wary of her. She sticks out like a "sore thumb" given she is completely different by the ranchers. They, therefore, treat her as if she is not wanted around (which she is not), constantly telling her that she does not belong in the bunk house.
Lastly, Curley's wife is forced to stay in the house all of the time. Curley is worried that she will get into trouble, given she is the only woman around, and he forces (or does his best to force her) into isolation. She states this openly in chapter four:
Think I don't like to talk to somebody ever' once in a while? Think I like to stick in that house alla time?"
Overall, Curley's wife is discriminated against throughout the novel (up until her death). Steinbeck does nothing to hide this fact.
In page 54 curleys wife is basically not wanted as she tries to make conversation with george.
Thank you so much :)