I am not sure the exact purpose of the question. But if you mean, can any of these tragedies entirely replace another, I would say no. While I prefer Macbeth to the other two tragedies, each tragedy, although following a specific formula, has something different to offer.
Macbeth discusses the nature of power and the influence of evil or perhaps even just the influence of suggestion. The playing of the sexual power of the women, Lady Macbeth and the witches, is very uncommon especially for the time period.
Hamlet deals with the idea of revenge and how consuming such a task can be. Hamlet becomes his own worst enemy, moreso than his uncle even is. Poor Ophelia is an innocent victim in his search for revenge. In addition, Shakespeare looks closely at the human flaw of indecisiveness and how our indecision can get us into more trouble than if we just choose and commit.
Finally, Othello can be looked at with a race issue lens. In addition, it again comments on power but in a different way than Macbeth. Instead of looking at the duty of a subserviant to his king (Macbeth to Duncan), it is more closely looking at the power of ambition and how someone's drive for power can lead to the loss of life. It also features an interesting web of lies that leads to numerous characters' deaths as well as others moral ruin.
So I think there is something to be learned from each of these plays. There are some overlapping ideas, sure, but it is certainly not redundant in any way.