It is reasonable to infer that Fitzgerald modeled the daily schedule and "general resolves" of young Gatsby (née James "Jimmy" Gatz) after those of Benjamin Franklin in his autobiography. The pathos, then, is that while Franklin rose to success, wealth, international prominence, and longevity by following his daily schedule and "thirteen virtues," Gatsby's rise is relatively short-lived because of the corruption of his dream.
Jimmy Gatz's schedule is more than a nod to Franklin's; in fact, Fitzgerald makes "study electricity, etc." the third entry in Gatz's daily schedule. Franklin has long been considered a role model for young Americans of modest means trying to work their way up from poverty through hard work and perseverance. He is certainly the epitome of the American Dream and a worthy role model for Jimmy Gatz.
Gatsby's departure from his Franklinesque pursuit of upward mobility seems to begin the day he meets Daisy Fay. After distinguishing himself in WWI, he has to acquire wealth quickly to have any hope of winning her, and this is when he turns to criminal enterprise to make his fortune.
The close of Gatsby's life indeed injects a mournful tone into the novel when the reader understands that had Jay Gatsby not met Daisy Fay, his pursuit of success and upward mobility might have echoed the trajectory of Franklin's, and he could have been a successful, self-made man through honest work.