In "going international" with regard to business, my first question would be in what state is another country's economy. The second question I would ask is how strong the U.S. dollar is in that country: that would indicate how far your dollar would go (if you're in the U.S.) (The same concern would exist if you were starting in a country other than the U.S.—how strong is your country's currency compared to other countries?)
There seems to be a great deal of interest in drawing companies operating in other countries back to the U.S. to strengthen the economy by keeping U.S. dollars here and creating jobs for people here. The government has been talking about incentives to keep businesses on U.S. soil. I would also look into things like this.
I would also study another country's laws with regard to foreign countries operating on their soil, and what kinds of things might interfere with being successful somewhere else. For instance, if there is civil war or there are drug wars, no matter how inexpensive labor and manufacturing costs might be, there are many more concerns that could hinder success...including not only loss of financial investments, but also life.