From which Shakespearean work does the quote below come from and what are the circumstances in which it is spoken? Out, damned spot, I say!

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This line is one of the most famous lines in Shakespeare's works.  It is from the play Macbeth.  It is spoken in Act V, Scene 1 and is spoken by Lady Macbeth.

The line is spoken while she is sleepwalking.  In this scene, the Gentlewoman and a doctor...

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This line is one of the most famous lines in Shakespeare's works.  It is from the play Macbeth.  It is spoken in Act V, Scene 1 and is spoken by Lady Macbeth.

The line is spoken while she is sleepwalking.  In this scene, the Gentlewoman and a doctor are watching her because the Gentlewoman has been worried about Lady Macbeth's sleepwalking.

What is going on is that Lady Macbeth is so guilty about her role in all the killing that Macbeth has done that she feels like she has blood on her hands that can't come off.

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