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During the century stretching from 1450 and 1550, the Spanish were very busy conquering the INca and the Aztecs and taking control of much of South and Central America as well as stocking the colonies with slave labour after smallpox and other diseases wiped out millions of the natives.
The Ottomans were also busy expanding in areas all around the Mediterranean and the Black Sea. Then enter Suleiman the Great and his massive conquests in Europe and the Ottoman's rise to supremacy in that area was complete.
In some ways, both empires peaked around this time, particularly in terms of their land holdings.
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