In terms of ageing and infertility, I can see this in Macbeth. For example, though Lady Macbeth states that she has nursed a child, but no children are mentioned in the play.
I have given suck, and know(60)
How tender ’tis to love the babe that milks me (I.vii.60-61)
We can assume she has had a child but no longer does. If she had one child and no more, this might literally indicate infertility. That Macbeth is enraged that Banquo's "issue" will become kings. He has lost his eternal soul (in killing Duncan) and will not be able to pass what he has murdered to get, to his children.
The ageing motif applies to how worn and beaten down Macbeth and Lady Macbeth are after they have murdered the King, and Macbeth has assassinated Banquo and Macduff's family. The vibrancy of this couple has fallen off, and they shuffle along, tired and unsatisfied.
There is also a sense of infertility (and regeneration) figuratively, as Macbeth's efforts to become powerful and take the throne do not yield any "fruit." He is hated and feared, not loved and respected as Duncan once was. His kingdom will not endure after his death, and no one will offer up praise or prayer at his death.
It is interesting when you note the trees that are hewn down to cover Malcolm's soldiers as they move on Macbeth and his castle. The landscape of the play has been very grey—as has the mood since the witches opened things "in the fog and filthy air" at the beginning. It is only with Malcolm that change arrives, and it is announced with a vibrant green, which may symbolize fertility and regeneration as a new king will soon be crowned and Scotland will have new life.