Consider the distance formula between two points. The formula is:

`d = sqrt((x_2-x1)^2 + (y_2 - y_1)^2 )`

Then, let  `d_1` the distance between (0,0) and (x,y) and 

 `d_2`  the distance between (4,-2) and (x,y).

Since  `d_1` and `d_2`  are equidistant ,  set  `d_1` ` ` and `d_2`  equal to each other.

                               `d_1 = d_2`                

   `sqrt((x-0)^2 + (y-0)^2) = sqrt((x-4)^2 + (y - (-2))^2 )`  

                `sqrt(x^2+y^2) = sqrt((x-4)^2 + (y+2)^2)`      

Then, square both sides.

                  `x^2 + y^2 = (x-4)^2 + (y+2)^2`  

Expand right side. Use FOIL method.

                  `x^2 + y^2 = x^2 - 4x - 4x + 16 + y^2 + 2y + 2y + 4`

                 `x^2 + y^2 = x^2 - 8x + 16 + y^2 + 4y + 4`        

                 `x^2 + y^2 = x^2 - 8x + y^2 + 4y + 20`    

Move all the terms with exponent 2 on one side of the equation.

    `x^2 + y^2 - x^2 - y^2 = -8x + 4y + 20`  

                          ` 0 = -8x +4y + 20`

Since -8, 4 and 20 are all divisible by 4, then divide both sides by 4 to simplify.

                        `0 = -2x + y + 5`

Then, we may express the above expression in slope intercept form.

                        `y = 2x - 5`            

Hence, the locus of the point is y = 2x - 5.