Blanche Dubois in Williams' A Streetcar Named Desire could be called "The Queen of Denial," as you suggest, but the label probably doesn't do her justice and is probably like most labels: simplistic and only partially true. Williams himself suggested that Blanche should arouse pity for her and on her behalf in the audience. She is, of course, a character representing a failed human being, but so is every other character in the play. Some would say that is the state of human existence.
That said, Blanche's denials come into play in the discrepancy between her outward appearance and dialogue and actions, and her inner desires. While she talks to others about her reputation and plays coy with her male suitor, and while she appears to be horrified by her behavior in the past concerning her desires, her flirting with Stanley and her behavior toward the young man who comes to the apartment demonstrate that she still feels those desires and is willing to act on them when opportunities arise.
Thus, she attempts to deny her desires in order to be successful, or at least safe. As she tells the doctor at the close of the play, she has always relied on the kindness of strangers [men, it is implied].
Of course, she also denies the coming of her utter downfall, when she continues to insist that she is going to be rescued by her old, male but now married, friend.