Explain this quote from act 4, scene 3, of Macbeth: "but I must also feel it as a man: I cannot but remember things were, That were most precious to me . . . . They were all struck for thee!"  

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Malcolm appreciates that Macduff's understandably upset after having his whole family wiped out by Macbeth. But he also wants him to concentrate on the bigger picture. Yes, this is a personal matter—a deeply personal matter—but it's also a political one. There's a tyrant to be overthrown and a kingdom to be won and that should be Macduff's main focus, as with all of Macbeth's opponents.

Macduff understands this and instead of crying, pledges to defend Scotland like the honorable man he believes himself to be. But in the immediate aftermath of hearing the sad news of his family's murder, he cannot help but cry at the fate to which he abandoned them. Malcolm urges him to be strong, to fight back the tears like a man. Macduff replies that he will do so, but that he can't just ignore the strong feelings he still has for his family. The implication is that it's just as manly to grieve for one's family as it is to grab hold of a sword and exact revenge for their deaths.

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In this passage, Macduff is reacting to the horrible news, brought by Ross, that Macbeth, fearing the witches' prophecy to beware of Macduff, has had his family killed in his absence (hoping, of course, to kill him as well). He is struck with grief, and Malcolm, while sympathetic, tells him to "dispute it like a man," meaning that he should take revenge on Macbeth. Macduff replies that he will gain revenge in a manly way, but that he could not help but grieve as a man who has lost his family. All of the things that meant the most to him, he says, were taken from him, and he realizes, talking to himself, that they were "struck for thee," meaning that they were killed because Macbeth was after him. The fact that, as a warrior, a husband, and a father, he was in hiding and was unable to protect his family devastates him all the more. It is at this point that Macbeth has an implacable enemy in Macduff, thus, in an ironic way, helping to fulfill the witches' prophecy.

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