Solubility is a term describing the capability of solutes to be dissolved in water. Cholera, Vibrio cholerae, is a living bacteria that can affect person who ingested food contaminated with Cholera. We cannot really determine the solubility of Cholera in water.
Cholera can thrive in water as they flow freely and suspended in it. They use their flagella in order for them to move. However, there is a certain limit for intoxication in humans. About one hundred million cholera bacteria should be ingested to have an effect in a normal healthy adult. Generally, it would be very hard for them to thrive in the stomach where there is a very high acid concentration. High acid concentration can dissolve the walls of the bacterium which can cause death.