In Edward's view, what must sinners do to be spared God's wrath?
Jonathan Edwards was a fiery British theologian whose most famous sermon, "Sinners in the Hands of an Angry God," is one of the classic works to come out of the Great Awakening, a movement in the Christian Community that took place between 1830 and 1855.
In reading the sermon, which can be accessed with a search in any search engine, you will see that the gist of the sermon is the point that sinners, all sinners, deserve to suffer for an eternity in Hell.
At any moment, according to Edwards, Hell awaits and Satan is ready to take anyone.
According to Edwards, Christ extends an unending invitation to the sinner and (in answer to the question that you posed above) the only thing that can possibly save the sinner from the wrath in store is to return to Christ in faith.