Do the antibodies present in blood at the time of blood transfusion destroy the recipient's blood cells?
For instance if we are transfusing O blood having anti A bodies to a patient of group A will the anti bodies destroy the blood cells of patient?
It depends on the type doing the donation and the type receiving the donation. If you are donating type "O" blood, type O is called the universal donor because it has neither A nor B antigen on its blood cells surface. So it can be donated to types A, B, or AB without significant harm to the individual receiving the transfusion. On the other hand, an individual with a type "O" blood type can only receive blood from a person with type O. Blood typing has a long and storied history, dating back as early as the 1500s, when one of the Popes was administered what was considered a blood transfusion from three young boys. The transfusion was administered orally, as this was before the time before knowledge about blood and circulation was common. The Pope and the three young boys all died, as this method of transfusion had no appreciable positive health effects.
The thing which are responsible human blood differenciation is ANTIGENS, ANTIBODIES. But if the inappropriate blood transfusion is done it can lead to CLOTTING of blood.