Jews were readily accepted in only one colony, South Carolina. The Lord Proprietors of South Carolina had grandiose schemes of getting rich quick from the sale of deer hides, Indian slaves, and later rice and indigo. They saw the key to this prosperity as encouraging settlement to anyone regardless of religious preference, thus Jews were welcomed into the State. The earliest Jewish congregation and synagogue were established in Charleston, S.C.
Jews were not welcome in other parts of the colonies, including Jamestown, where members were expected to pay nominal service to the Anglican Church. In New England, no one except those who subscribed to their Puritan beliefs were welcomed, they even hanged a group of Quakers once who refused to leave. Obviously, non-believers were heartily NOT welcomed. Anti-semitism was alive and well in Europe, so Jews there suffered from time to time; but in the Americas, only in South Carolina were they allowed to emigrate at all until the late nineteenth century.