Yes, the Indians who survived the massacre exacted revenge for the events that took place at Sand Creek. Warriors from the Sioux nation joined the Cheyenne and Arapaho in making plans to fight the whites invading their territory. The response given to James Beckwourth when he found the council of war chiefs summarized their attitude following the Army's actions at Sand Creek.
The white man has taken our country, killed all of our game; was not satisfied with that, but killed our wives and children. Now no peace....We have raised the battle ax until death.
Beginning in January, 1865, the Indians raided settlements, attacked wagon trains, destroyed telegraph poles and lines, and disrupted supply lines intended to bring provisions to the whites in the Platte River valley and along the plains. The battle continued until the last of the tribes were exiled, forced to leave their historic claims by treaty with the whites.