In 1885 Edith Wharton married Edward(Teddy)Wharton and according to most biographies her marriage was very unhappy. In 1908 Teddy had a nervous breakdown, and then she found out that her husband had taken money from her to support and keep a mistress. In 1912 Edith divorced her husband. She had no children and she never got married again.
She did have an affair with Morton Fullerton while still married, but had no children by either man.