To get you started on creating a lesson plan to teach the concepts of prokaryotic versus eukaryotic cells and unicellular versus multicellular organisms, let's brainstorm some of the best ways to present and illustrate the similarities and differences between these groups.
One of the best ways to begin is to present two diagrams to the class, one of a prokaryotic cell and one of a eukaryotic cell, and to ask the students to identify the similarities and differences between the two. They might come up with ideas about the shape of the cells as well as the structures within them.
At the point, provide a short lecture about the cells, defining prokaryotic and eukaryotic as two types of cells in living beings that both contain DNA, cytoplasm, ribosomes, a cell membrane, and a cell wall. Carefully define these terms so that the students understand clearly what they mean.
Now, for prokaryotic cells, mention that these are unicellular only (like bacteria), and concentrate especially on how they lack a nucleus and other organelles. You might talk about how prokaryotic cells have a nucleoid instead of a nucleus and how the DNA floats freely. Be sure to point out the other parts of these cells.
Now, turn your attention to the eukaryotic cells, and explain how these can be unicellular but are usually multicellular (like plants and animals). You should focus especially on the various structures found in these cells, defining terms like nucleus, mitochondria, and Golgi bodies.
It would greatly help to use a power point presentation to illustrate this lecture so that students can see the cells and their parts. The slides should also contain brief definitions of the parts of the cells as needed.
To allow the students to use their new information and practice with it (making it their own), you might present them with blank diagrams of each cell type and ask them to work alone or in pairs to label the parts and identify the cells as prokaryotic or eukaryotic. Alternately, if the students have access to a computer, you might direct them to the Cells Alive website, where they can view animations of the cell types and components. There are also worksheets, games, and puzzles available on this site to enhance student learning.
Assessments for this lesson might include multiple-choice questions about the various types of cells and structures and blank diagrams for the students to fill in and explain.