We can see this misogyny when he has Antigone brought to him to answer charges that she buried Polyneices. He is threatened by her - by the thought that she would disobey him, being a "proud girl, in insolence well-schooled." He says that if she remains "Unpunished, I am woman, she the man." How awful...to be considered a weak and womanish ruler! Later, right before Ismene comes in, he tells Antigone, "Die then, and love the dead if thou must; No woman shall be the master while I live."
Re: Ismene - Creon calls her in and instantly assumes that she is also a "viper unperceived," like Antigone, and that she helped Antigone bury Polyneices. Of course, this might not be misogyny so much as paranoia, but I wondered if Ismene had been a man (another brother to Antigone), would he have reacted the same way?
One thing I found fascinating, and that ties in nicely to a previous question concerning what Creon fears the most, is that when he personifies Anarchy, he refers to Anarchy as a female:
"What evils are not wrought by Anarchy!
She ruins States, and overthrows home,
She dissipates and routes the embattled host;
While discipline preserves the ordered ranks."
Something he hates and fears the most - Anarchy - he makes into a woman.