Compare somatic and gametic mutations. What is the difference of that?not too long pls

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ako6777 eNotes educator| Certified Educator

In general somatic mutations, also known as acquired mutations, can occur in any cell of the body as long as it takes place after conception and is not destined to become a germ cell.  This is because the mutations are not possible in germ cells, which are also known as the sperm and the egg.  Thus the mutation is not inheritable.   Some examples of somatic mutations are:

  • When someone is exposed to too much sun and develops cancer
  • Smoking cigarettes and developing lung cancer.
  • Mesothelioma

Gametic mutations, on the other hand, are mutations that occur in germline cells (sperm and egg).  Due to this, the mutations are able to be passed on from one generation to another.  One of the most famous gametic mutations is hemophilia.


besure77 eNotes educator| Certified Educator

Somatic mutations are mutations that occur in cells of the body not including those cells that are responsible for reproduction. This means that these mutations do not happen in the sperm cells or the egg cells. Since they do not occur here, it is not possible for offspring to be born with this mutation. An example of a somatic mutation would be brown spots in the iris of the eye.

Gametic mutations occur in germline cells. This means that they may be passed down from generation to generation. Sometimes these mutations may not even be noticed. An example of a gametic mutation would be albinism.