These colonies differed in a number of ways. These ways included:
- Ethnic/national background. Massachusetts was essentially settled only by people from England. In Pennsylvania, there were also Scots-Irish people and Germans.
- They differed economically to some extent. Massachusetts was much more dependent on the sea with shipping and fishing as major industries along with rum distilleries using molasses shipped in from the Caribbean. By contrast, Pennsylvania was dominated by farmers, largely producing grain.
- Religion. Massachusetts was settled by the Puritans and was meant to be dominated by them. Pennsylvania, of course, was settled by Quakers and was meant to be a much more tolerant and religiously diverse colony.