Cloud Atlas by David Mitchell is a pretty singular novel. Finding a book you enjoy the same way depends somewhat on which aspects of Cloud Atlas move you. If you find the idea of the family saga engaging (which Cloud Atlas is not but is similar) 100 Years of Solitude by Gabriel Garcia Marquez and Buddenbrooks by Thomas Mann are two of the most classic, literary family sagas ever written. The writing style in both will be very different from David Mitchell, however.
If the writing style is what draws you, David Mitchell has published six books besides Cloud Atlas including number9dreamand Ghostwritten, which trots around the globe.
On a quick search on goodreads, people who liked Cloud Atlas also liked Life of Pi, Oryx and Crake, The Road, The Wind-Up Bird Chronicle, and Dune. That is a pretty wide-ranging list, but if you read the descriptions of each book it is likely one would stand out to you.
As an outside of the box suggestion, Jo-Jo’s Bizarre Adventure is a long-running manga (and anime) tracking the Joestar family from generation through generation. Each member shares a birthmark on their neck. This is a zany story and not for just anyone, as it involves fighting vampires, strange turns of plot, and magical powers.