I think of nitrogen narcosis and/or the solubility of gases in the human body using Boyles Law. Pressure is inversly related to volume. As one goes from areas of low pressure to high pressure, gas bubbles in the body will expand or contract accordingly causing, for example, embolisms, membrane expansion or discomfort (ear drums, flatualism, labored breathing etc). Temperature and pressure are directly proportional as related by Charles law. Heated air is less dense and affects oxyen, nitrogen and water content in air. The above discomforts and fixation of the gases in the bronchaiel tubes of the lungs and blood could be unbalanced, as a result.