It's no exaggeration to say that Andrew Jackson's tenure as president was an unmitigated disaster for Native Americans. Jackson shared the widespread racial prejudice of the day toward indigenous peoples and believed that they should be forced to vacate their ancestral lands to make way for the white man, their supposed racial superiors. To that end, Jackson embarked upon a policy which today would be described as ethnic cleansing: that is to say, forcibly removing a specific racial group from a particular territory and replacing them with those of a different race or culture.
To that end, Jackson signed the Indian Removal Act of 1830, which gave him widespread powers to grant unsettled lands west of the Mississippi in exchange for native lands within existing state borders. Some tribes went along with the policy, albeit reluctantly. However, many more defied the new legislation—most notably the Cherokee, whose resistance was broken by armed force. In the ensuing forced removal of the Cherokee to the west of the Mississippi, something like four thousand men, women, and children perished on the long, hard march, leading to this shameful event in American history being christened the Trail of Tears.