Yes. Alienation is something that many people deal with today, including alienation from another individual, from government, from society as a whole, etc. Alienation is also one of the most common themes in world literature. Nearly every text deals with a sense of separation, be it one character from another, or an entire culture from the world.

Alienation in politics is a huge issue today. On one side, politicians seek to be careful in every word they say, tryng to win over as many voters as possible. This may be less true now than in the past, because the country is more divisive today, politically speaking. But generally, those running for office seek to placate as many groups as possible. It's rather ironic though, because the very process of politics alienates those involved from their constituents. In America, most politicians at a national level live in Washington D.C. most of the year. At the state level, they live in the state capital. Thus, they are removed from the day-to-day concerns of the people they should be representing.

This is why so many people feel disconnected from the government. Some take the viewpoint that the government does nothing concrete for them, so they see no purpose in it. Others feel that their voices are not heard or completely ignored. Or, a law may be passed that affects one group positively, and another negatively. This will probably make the affected group feel alienated from the state. In much the same way, John is completely removed from the World State in the novel. He cannot see the benefits of what the government does for its citizens, and therefore feels isolated and alone.