You would set this problem up as an order of operations problem.
First you eliminate parentheses
Second you eliminate exponents
Third you multiply and divide in order from left to right
Fourth you add and subtract in order from left to right.
Here is a sentence to help you remember what to do first.
Please excuse my dear Aunt Sally.
(parentheses) exponents multiply and divide add and subtract
reorder terms (when dividing fractions use the reciprocal of the second fraction and multiply them)
multiply fractions (you could cross multiply)
add fractions (be sure that the denominator for both fractions is the same, and add the numerators)