SAMe (Encyclopedia of Mental Disorders)
SAD see Seasonal affective disorder
Sadism see Sexual sadism
SAMe (or S-adenosyl-L-methionine) is a naturally occurring chemical that is found throughout the entire body. It is involved in many chemical reactions that are necessary for life. SAMe is available as a natural dietary supplement that can be found at some pharmacies or health food stores, and can be purchased without a prescription.
People take supplements of SAMe for many reasons including its possible antidepressant effects. Some evidence suggests that taking SAMe can improve symptoms of depression within two weeks, which is considerably faster than the time it takes for oral antidepressant prescription drugs to work. (Prescription antidepressants often take a minimum of two weeks for patients to begin noticing any effect, and many take four to six weeks.)
SAMe is a specific form of the amino acid methionine, a substance that, when not metabolized properly, allows homocysteine to build up in the blood. SAMe is also an antioxidant, a substance that...
(The entire section is 782 words.)
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Ademetionine (Encyclopedia of Alternative Medicine)
Ademetionine, also known as SAMe, is a specific form of the amino acid methionine known as S-adenosyl-methionine. The body manufactures it, and it is found in most tissues of the body. Ademetionine is essential for the formation of glutathione, a water-soluble peptide that helps the body fight free radicals. SAMe also helps the liver to process fats (protecting against a fatty liver) and is believed to play a role in protecting the body from heart disease. SAMe is a methyl donor, which means that it provides other molecules with methyl groups that are critical to their metabolism. In general, ademetionine raises the level of functioning of other amino acids in the body. Severe deficiencies of SAMe can cause problems with other important body functions, such as secretion of important hormones like melatonin, which plays a key role in regulating sleep and circadian rhythms.
The synthetic formula of ademetionine has been hailed as an anti-aging formula because it is such a powerful antioxidant. Antioxidants are substances that counteract the damaging effects of free radicals in human tissue. Ademetionine has been widely popularized recently, but it is not a recent discovery. In fact it was discovered in Italy in 1952, and has been widely researched over the past few decades....
(The entire section is 1278 words.)