Acute Erythroblastic Leukemia (Encyclopedia of Cancer)
Acute erythroblastic leukemia, also called erythremic myelosis, DiGuglielmo syndrome, or erythroleukemia, results from uncontrolled proliferation of immature erythrocytes (red blood cells).
Acute erythroblastic leukemia, a variant of acute myelocytic leukemia, originates in the blood and in the bone marrow. In this form of leukemia, a large number of abnormal, immature red blood cells are produced. The advanced phase is also called the blast crisis. At this stage, over 50% of the cells in the bone marrow are immature malignant cells (also called blast cells or promelocytes).
There are no statistics available for this rare form of cancer.
Causes and symptoms
The causes of acute erythroblastic leukemia are largely unknown. However, acute erythroblastic leukemia constitutes 10-20% of leukemias secondary to radiation, alkylator therapy, or overexposure to benzene.
Patients with this type of leukemia have less than the normal amount of healthy red...
(The entire section is 1268 words.)
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