Acetazolamide (Encyclopedia of Neurological Disorders)
Acetazolamide (a-set-a-ZOLE-a-mide) is a carbonic anhydrase inhibitor. Carbonic anhydrase is an enzyme that shifts the rate of reaction to favor the conversion of carbon dioxide and water into carbonic acid, bicarbonate ions, and free protons. Carbonic anhydrase activity is key to the regulation of pH and fluid balance in many different reactions throughout the body.
Fluid buildup can alter the shape of the eye and cause pressure on the optic nerve. Clinically, this condition is described as glaucoma. Inhibition of the enzymatic work of carbonic anhydrase activity (e.g., through the action of a carbonic anhydrase inhibitor) can lower fluid pressure in the eye.
Acetazolamide is used to treat a number of disorders, including the control of epileptic seizures in those individuals who suffer epilepsy.
Acetazolamide is also used to treat non-neurological disorders such as glaucoma (acetazolamide decreases pressure in the eye), and to reduce the symptoms of edema (an excess storage of water by the body that leads to localized swelling or puffiness) and altitude sickness.
Acetazolamide is prescription medication and is available only with a licensed physician's prescription. Acetazolamide is...
(The entire section is 716 words.)
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