Tumor Marker Tests
Definition
Tumor markers are a group of proteins, hormones, enzymes, receptors, and other cellular products that are overexpressed (produced in higher than normal amounts) by malignant cells. Tumor markers are usually normal cellular constituents that are present at normal or very low levels in the blood of healthy persons. If the substance in question is produced by the tumor, its levels will be increased either in the blood or in the tissue of origin.
Purpose
The majority of tumor markers are used to monitor patients for recurrence of tumors following treatment. In addition, some markers are associated with a more aggressive course and higher relapse rate and have value in staging and prognosis of the cancer. Most tumor markers are not useful for screening because levels found in early...
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