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I'm developing a study concerning probiotics. I'm interested if there are prerequisites for human use.

Yes there are prerequisites for probiotics and they are:

- they have to have human origin

- they have to resist to biliary and pancreatic secretion, stomach acidity and methods of manufacturing products

- theyhave to stick on intestine epithelial cells in order to resist to intestine movements and to colonize, at least temporarily, the intestine

- to product antimicrobial substances operative against pathogenic bacteria