Home > Encyclopedia of Neurological Disorders > Pick Disease

Definition

Pick disease is a rare neurodegenerative disorder that affects pre-senile adults. It is characterized by atrophy of the tissues in the frontal and temporal lobes of the brain and by the presence of aggregated tau protein that accumulates in Pick bodies in the neurons of the affected regions. Named for the German physician who studied patients who with the disease, Pick disease is grouped together with other non-Alzheimer's dementias, under the category of frontotemporal dementia (FTD), which is now the preferred term for Pick disease. FTD is classified by the Diagnostic and Statistical Manual of Mental disorders, Fourth Edition (DSM-IV) as a Dementia Due to Other General Medical Conditions.

Description

The disease is named after the German physician, Arnold Pick, but it was not named by him. German psychiatrist and...