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Definition

The lipase test is a blood test performed to determine the serum level of a specific protein (enzyme) involved in digestion. Lipase is an enzyme produced by the pancreas, which is a large gland situated near the stomach. Lipase works to break down a certain type of blood lipid (triglycerides) into fatty acids.

Lipase appears in the blood together with another enzyme called amylase following damage to or diseases affecting the pancreas. It was once thought that abnormally high lipase levels were associated only with diseases of the pancreas. Other conditions are now known to be associated with high lipase levels, especially kidney failure and intestinal obstruction. Diseases involving the pancreas, however, produce much higher lipase levels than diseases of other organs. Lipase levels in pancreatic disorders are often five to 10 times higher than normal.

Purpose

The lipase test is most often used...