Immunoglobulin Deficiency Syndromes
Definition
Immunoglobulin deficiency syndromes are a group of immunodeficiency disorders in which the patient has a reduced number of or lack of antibodies.
Description
Immunoglobulins (Ig) are antibodies. There are five major classes of antibodies: IgG, IgM, IgA, IgD, and IgE.
- IgG is the most abundant of the classes of immunoglobulins. It is the antibody for viruses, bacteria, and anti-toxins. It is found in most tissues and plasma.
- IgM is the first antibody present in an immune response.
- IgA is an early antibody for bacteria and viruses. It is found in saliva, tears, and all other mucous secretions.
- IgD activity is not well understood.
- IgE is present in the respiratory secretions. It is an anti-body for parasitic diseases,
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