Personally I believe that there was, at some point, the 'begining' where the 'origional' Jane was born from normal parents that then started the cycle. Its like a circle with a little tail coming out of it.
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This is certainly possible. After all, there is a lot of time travel involved in the story but at some point there has to have been a beginning. A female makes sense, since the female was impregnated.
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