What should I understand about this phrase: "Lytic lesion in L2 Vertebral body?" This is an MRI report.

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A lytic lesion is an area of damage on a bone.  The damage might be just a weakening of the bone or perhaps a small hole in the bone.  It is called a "lytic" lesion because it is caused by a process called "osteolysis".  This is the process by which cancer cells metastasizes, meaning changes and spreads. 

A lytic lesion in the L2 verterbral body refers to a weakened area of bone in the lumbar region of the spine - the L refers to lumber, the 2 refers to the second disc of that region.  The lumbar is the lower back.

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