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Sarcoidosis is a disease in which clumps of inflammatory cells develop in different areas of the body. It most commonly affects the lungs, eyes, skin, and lymph nodes.
Doctors believe sarcoidosis results from an abnormal immune response. The course of the disease varies from person to person. It often goes away on its own, but in some people symptoms of sarcoidosis may last a lifetime.
There are many symptoms of sarcoidosis such as difficulty in breathing, coughing, fever, weight loss, or watery eyes.
Possible causes of sarcoidosis are genetic predisposition or an immune system reaction to a toxin.
Sarcoidosis is a chronic inflammatory, immunologic disease of idiopathic etiology which affects almost all body systems and structures. It causes a generalized lymphadenopathy(edema of the lymphatic system). The lungs are also frequently affected. Inflammation of the lung parenchyma leads to dyspnea due to decreased gas exchange.
Small granulomatus lesions are formed on affected tissues, these can be visualized on chest x-ray. Often, more than one organ at a time develop the granulomas. Lesions on the pituitary gland can lead to diabetes insipidus.
The disease may be in "active" phase or "nonactive" phase. During nonactive phase the patient is well maintained on oral steroid therapy. Active phases may result in acute respiratory failure to do overwhelming inflammation and pulmonary edema.
Sarcoidosis is an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands.
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