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What is Hemophilia?
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Hemophilia is in most cases an inherited disorder which passes from parents to their offspring. In hemophilia, the blood in the person who has it cannot clot on its own. When blood vessels of normal people get injured, various proteins make the platelets stick together and form a plug that prevents blood from flowing out and the blood vessels heal. In hemophiliacs the clotting factors are not present. This results in blood continuously flowing out of a damaged blood vessel and can potentially kill the person. The person has to be given clotting factors through injections to make the flow of blood stop.
Posted by william1941 on September 29, 2010 at 1:51 PM (Answer #1)
Hemophilia is known as bleeder's disease, and is carried on the X chromosome. Males have one X and females have two X chromosomes. If capital X represents a normal gene on the X chromosome and X- represents the gene for hemophilia, there are several genotypes to consider. In males, they can be XY(normal male), or X-Y(bleeder male). In females, XX(normal female), X-X(carrier female, with one normal and one hemophilia gene) and X-X-(female hemophiliac). The chances of a female getting a hemophilia gene from each parent is low. However, since males only get one X from their mother, if it contains the hemophilia gene, then they would get a disease phenotype. This disease is the inability to form a blood clot when a blood vessel is injured.
Posted by trophyhunter1 on September 29, 2010 at 9:53 PM (Answer #2)
Blood clotting is a very complicated multi step process with many substances involved. In hemophilia A, the most common form of the disease is a genetic inability to produce Clotting Factor VIII. The clotting cascade cannot be complete without it.
Posted by ashkuehn on March 6, 2011 at 11:48 PM (Answer #3)
Hemophilia is a blood disorder that causes a person to bleed non-stop once they get a cut, bruise, or any other type of abrasion.
Hope this helps! :D
Posted by mirmirnotez on November 25, 2012 at 1:19 AM (Answer #4)
High School Teacher
Hemophilia is a blood disorder that is almost always inherited, although other certain health factors can cause similar symptoms. The main issue with hemophiliacs is that their blood refuses to clot, or has difficulty doing so anyway, so that ordinary cuts and bruises that a person gets in the day-to-day happenings of life can actually be life threatening. A person can bleed to death in some circumstances, and if they cannot get medical attention quickly enough to have clotting factor injected into their bloodstream.
In the old days of European monarchs, so much intermarrying occurred among royal families, that by the 1800s most of them had hemophiliacs among their family members.
There are several varieties of hemophilia, and most are differentiated by the lack of a different clotting factor that ends with the same result of profuse bleeding and bruising.
Posted by brettd on September 29, 2010 at 1:08 PM (Answer #5)
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