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What is the enzyme that converts fumarate to L-malate.

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greynose | Student, Undergraduate | Honors

Posted August 2, 2011 at 9:18 PM via web

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What is the enzyme that converts fumarate to L-malate.

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jgeertz | College Teacher | (Level 1) Associate Educator

Posted September 15, 2011 at 11:16 PM (Answer #1)

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Enzymes can be defined as substances produced by a living organism that act as catalysts in biochemical reactions. That is to say they speed up or increase the rates of specific biochemical reactions.

The enzyme that converts fumarate to L-malate is named fumarase or fumarate hydratase (FH). This enzyme is located in the mitochondria and cytoplasm of all eukaryotes.

Fumarase's job in the mitochondria is to make energy for the cell through the citric acid cycle, also known as the Kreb's cycle.

Fumarase's job in the cytoplasm may be to repair DNA double-strand breaks in the nucleus as well as to suppress tumor growth.

 

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