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Is Parkinson's disease passed down through genes?

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mcy77 | Student, Undergraduate | eNoter

Posted May 28, 2010 at 2:47 AM via web

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Is Parkinson's disease passed down through genes?

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dano7744 | College Teacher | (Level 2) Educator

Posted May 28, 2010 at 3:17 AM (Answer #1)

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Yes, it can be genetic but similar to other genetic disorders, it may skip one or more generations. If it runs in your family you may be predisposed to contracting the illness at some point but this does not mean that you will definitely fall victim.

Parkinson disease is a chronic neurological disorder that most commonly affects one after the age of 50 but can strike at almost any age. It results from a deficiency of the neurotransmitter Dopamine in the brain. This leads to an over-stimulation of skeletal muscles. Signs and symptoms include trembling, muscle rigidity, and unsteady gait. A few treatments exist but limited results are seen.

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giorgiana1976 | College Teacher | Valedictorian

Posted May 28, 2010 at 2:57 AM (Answer #2)

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Parkinson's disease has unknown origin. There are invoked a specific hereditary predisposition, which would still only play a minor role, and, recently, the environmental factors, village-related as the influence of toxins like pesticides, for example.

Instead of, the disease mechanism is known: it is a degeneration which affects the nerve cells of a core central  (gray matter located inside the brain) called the locus niger, that entails a lack of secretion of dopamine, which is a neurotransmitter.

Parkinson's disease is a chronic neurological disease, that is characterized by tremors, stiffness and slowness of movement.

The disease starts to age of 55 years, sometimes immediately after a stress (surgery, emotional shock), often without reason and in a very gradual and insidious manner.

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paulagz | Student, Undergraduate | Honors

Posted May 28, 2010 at 3:54 AM (Answer #3)

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Research has indicated that 10-15% of Parkinson cases are family related which may point toward some genetic connection, but most researchers do not believe that Parkinson's has a significant heredity cause. The majority of cases are termed "sporadical" meaning no genetic connection is involved.  The latest research has focused on shared enviornmental factors to explain familial and cluster occurances.  There is also a viral connection being sturied.  It is now believed that there is more than one cause.

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hyderabadi | eNoter

Posted March 8, 2013 at 5:15 AM (Answer #4)

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Well. I suffer from Parkinson's and developed symptoms at 35 years of age. After conducting extensive research on the subject, I have reached the following conclusion:

Genetics: Is the basic foundation for Parkinsonism  Just like a degree qualifies you to get a job but does not guarantee it. Genetics lay the basic foundation to wether or not you are susceptible to the affliction.

Personality: Studies have shown that people who develop parkinsonism display a particular set of traits. highly focussed, intelligent and creative. Essentially, nature makes sure that you are well equipped to handle whats in store for you.

Environment: Stress, work, pollution are triggers that govern the rapid/slow onset of the symptoms.

Last but not the least, there are those who have induced parkinsonism by substance abuse. 

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